CURRENT ISSUE • JULY - DECEMBER 2016 • VOLUME VOL 19
 

ORIGINAL RESEARCH Download PDF

Differential Profile of OSA in Obese Kashmiri Patients of Northern India

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Abstract
ABSTRACT: Obstructive sleep apnea (OSA) and obesity are two interacting epidemics both with high prevalence and morbidity. Both epidemiologic and clinical studies suggest that the majority of patients with obesity also have OSA. OBJECTIVES: To assess the prevalence and severity of OSA in obese patients and also to assess the impact of OSA treatment on presenting symptoms and body weight. METHODS: We performed polysomnography studies in 74 consecutive patients with obesity that were referred from various sub-specialty clinics from July 2011 to August 2013. RESULTS: In our 74 obese patients, 59 (95.2%) had abnormal Polysomnography (PSG). Based on AHI (Apnea - Hypopnea Index) score, 3 (5.1%) patients had mild, 28 (47.5%) had moderate and 28 (47.5%) had severe OSA. The mean AHI of diabetic patients was significantly more than non-diabetic patients i.e 25.7 vs 19.7 (p = 0.001). Variables that significantly correlated with presence of OSA include age, gender, BMI, hypertension, diabetes and cardiovascular disease (p< 0.05), however on logistic regression only BMI, hypertension, and nocturia correlated with OSA. Overall 59% of diabetic patients showed improvement in their glycemic control as measured by HbA1c with CPAP treatment. Significant, moderate and mild categories of treatment response were respectively observed in 7%, 20% and 32% of patients.