Castleman's Disease - Unicentric Plasma Cell Variant - A Case Report with Review of Literature

Abstract

Castleman's disease (CD) is a rare disease with two identified forms. The localized form, often pauci symptomatic is characterized by enlargement of an isolated single lymphnode or lymphnode chain. Multicenteric form frequently presents with general signs. We report a patient who presented with cough and hemoptysis with imaging revealing right hilar lymphadenopathy. After thoracotomy, lymph node excision biopsy was done, histopathological examination revealed plasma cell - variant (PCV) of CD, a rare location for unicentric PCV of CD. JMS 2012;15(1):57-60.